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Gene Name:CYP2C9Uniprot ID:P11712 Molecular weight:55627. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. Gene Name:CYP2D6Uniprot ID:P10635 Molecular weight:55768. Gene Name:CYP3A5Uniprot ID:P20815 Molecular weight:57108. Gene Name:CYP3A7Uniprot ID:P24462 Molecular weight:57525. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids.

It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol). Gene Name:CYP2C8Uniprot ID:P10632 Molecular weight:55824. Epub 2008 Apr 15. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesisGene Name:CALM1Uniprot ID:P62158 Molecular weight:16837. The isoform alpha-1D gives rise to L-type calcium currents.

Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive trade drug name omega-conotoxin- GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA)Gene Name:CACNA1DUniprot ID:Q01668 Molecular weight:245138.

Epub trade drug name Nov 24. Biochem Biophys Res Commun. Show all enzymes and transportersThis project is supported by the Canadian Institutes of Health Research, Canada Foundation for Innovation, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility trade drug name supports a wide range of cutting-edge metabolomic studies.

It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, rooibos tea prevents calcium-dependent myocyte contraction and vasoconstriction.

Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. In addition trade drug name binding to L-type calcium channels, felodipine binds to trade drug name number of calcium-binding trade drug name, exhibits competitive antagonism of the mineralcorticoid receptor, inhibits the activity of calmodulin-dependent cyclic nucleotide phosphodiesterase, and blocks calcium influx through voltage-gated T-type calcium channels.

Felodipine is used to treat mild to moderate essential hypertension. Dihydropyridinecarboxylic acids and derivatives are compounds containing a dihydropyridine moiety astrazeneca inc a carboxylic acid involved. What are the possible side effects of felodipine (Plendil).

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Comments:

26.03.2019 in 13:21 Ия:
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02.04.2019 in 19:32 Рогнеда:
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